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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Faecal calprotectin ： ウィキペディア英語版 Faecal calprotectin Faecal calprotectin is a biochemical measurement of calprotectin in the stool. Elevated faecal calprotectin indicates the migration of neutrophils to the intestinal mucosa, which occurs during intestinal inflammation, including inflammation caused by inflammatory bowel disease. Under a specific clinical scenario, the test may eliminate the need for invasive colonoscopy or radio-labelled white cell scanning. ==Structure and function== Calprotectin is a 24 kDa dimer of calcium binding proteins S100A8 and S100A9.〔 The complex accounts for up to 60% of the soluble protein content of the neutrophil cytosol.〔〔 ''In vitro'' studies show that calprotectin has bacteriostatic and fungistatic properties, that arise from its ability to sequester manganese and zinc.〔 Calprotectin has two transition metal binding sites that form at the interface of the S100A8 and S100A9 monomers, and metal sequestration by calprotectin has been shown to be calcium dependant.〔 The complex is resistant to enzymatic degradation, and can be easily measured in faeces.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Faecal calprotectin」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.